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药用植物研究所

个人简介

宋经元,1969年生,籍贯湖北当阳,中药资源学专家,药用植物研究所研究员,博士生导师。1987年考入北京农业大学(现中国农业大学)植物生理生化专业,1991年获学士学位。1995-1998年、1999-2002年在黄金城赌城,澳门黄金城:生药学专业攻读硕士和博士学位,从事中药生物技术研究。1998年升为助理研究员。2004年进入美国北卡罗莱纳州立大学进行博士后研究,主要研究植物功能基因组。2006年升为副研究员。2011年升为研究员。2016年作为高级研究学者赴哈佛大学医学院访问。


主要研究方向

药用植物功能基因组,结构基因组与生物信息分析,细胞培养与活性成分生产调控,中药DNA条形码鉴定等。


代表性成果

黄金城赌城,澳门黄金城

图片

1. Gao R#, Lou Q, Hao L, Qi G, Tian Y, Pu X, He C, Wang Y, Xu W, Xu Z*, and Song JY*. Comparative genomics reveal the convergent evolution of CYP82D and CYP706X members related to flavone biosynthesis in Lamiaceae and Asteraceae. Plant J. 2022, 109(5):1305-1318. (IF=7.091)

2. Xu Z#, Li Z#, Ren F#, Gao R#, Wang Z, Zhang J, Zhao T, Ma X, Pu X, Xin T, Rombauts S, Sun W, Van de Peer Y*, Chen S*, and Song JY*. The genome of Corydalis reveals the evolution of benzylisoquinoline alkaloid biosynthesis in Ranunculales. Plant J. 2022, 111(1):217-230. (IF=7.091)

3. Pu X#, Li Z, Tian Y, Gao R, Hao L, Hu Y, He C, Sun W, Xu M, Peters RJ, Van de Peer Y, Xu Z*, and Song JY*. The honeysuckle genome provides insight into the molecular mechanism of carotenoid metabolism underlying dynamic flower coloration. New Phytol. 2020, 227(3):930-943. (IF=10.152)

4. Xu Z#, Gao R#, Pu X, Xu R, Wang J, Zheng S, Zeng Y, Chen J, He C, and Song JY*. Comparative genome analysis of Scutellaria baicalensis and Scutellaria barbata reveals the evolution of active flavonoid biosynthesis. Genomics Proteomics & Bioinformatics. 2020, 18(3):230-240. (IF=7.691)

5. Xu Z#, Pu X#, Gao R, Demurtas OC, Fleck SJ, Richter M, He C, Ji A, Sun W, Kong J, Hu K, Ren F, Song J, Wang Z, Gao T, Xiong C, Yu H, Xin T, Albert VA, Giuliano G*, Chen S*, and Song JY*. Tandem gene duplications drive divergent evolution of caffeine and crocin biosynthetic pathways in plants. BMC Biol. 2020, 18(1):63. (IF=7.431)

6. Pu X#, He C, Yang Y, Wang W, Hu K, Xu Z*, Song JY*. In Vivo production of five crocins in the engineered Escherichia coli. ACS Synth Biol. 2020, 9(5):1160-1168. (IF=5.110)

7. Xu Z#, Xin T, Bartels D, Li Y, Gu W, Yao H, Liu S, Yu H, Pu X, Zhou J, Xu J, Xi C, Lei H, Song JY*, and Chen S*. Genome analysis of the ancient tracheophyte Selaginella tamariscina reveals evolutionary features relevant to the acquisition of desiccation tolerance. Mol Plant. 2018, 11(7):983-994. (IF=10.812, ESI)

8. T#, Xu Z, Jia J, Leon C, Hu S, Lin Y, Ragupathy S, Song JY*, and Newmaster SG*. Biomonitoring for traditional herbal medicinal products using DNA metabarcoding and single molecule, real-time sequencing. Acta Pharm Sin B. 2018, 8(3):488-497. (IF=5.808)

9. Xu Z#, Peters RJ#, Weirather J, Luo H, Liao B, Zhang X, Zhu Y, Ji A, Zhang B, Hu S, Au KF, Song JY*, and Chen S*. Full-length transcriptome sequences and splice variants obtained by a combination of sequencing platforms applied to different root tissues of Salvia miltiorrhiza and tanshinone biosynthesis. Plant J. 2015, 82(6):951-961. (IF=5.468, ESI)

10. Li Q#, Li Y, Song JY*, Xu H, Xu J, Zhu Y, Li X, Gao H, Dong L, Qian J, Sun C, Chen S*. High-accuracy de novo assembly and SNP detection of chloroplast genomes using a SMRT circular consensus sequencing strategy. New Phytol. 2014, 204(4):1041-9. (IF=7.672)