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基础医学研究所

个人简介

王晨轩,1986年生,籍贯陕西富平,生物物理与物理化学家,基础医学研究所院研究员,博士生导师。2004年考入兰州大学国家理科化学基地班专业,2008年获得学士学位。2008年-2013年,在国家纳米科学中心物理化学专业攻读博士学位,从事表面物理化学研究。2013年进入威斯康星大学-麦迪逊校区进行博士后研究工作,主要研究单分子力学。2018年担任基础所生物物理系课题组长,副研究员,硕士生导师。2022年升任助理教授,博士生导师。


主要研究方向

疾病相关蛋白质组装与调控。发展新颖的物理、物理化学方法用于生物大分子的结构测定,在单分子水平理解蛋白质的折叠、组装结构和过程,认识蛋白质折叠组装过程中的相互作用本质与调控规律。


代表性成果

黄金城赌城,澳门黄金城

图片

1.Lanlan Yu#, Ruonan Wang#, Tao Wen#, Lei Liu, Tao Wang, Shuli Liu, Haiyan Xu*, Chenxuan Wang*, Peptide binder with high-affinity for the SARS-CoV-2 spike receptor-binding domain, ACS Applied Materials & Interfaces, 2022, 14(25), 28527–28536. (IF=10.383)

2. Yan Zhao#, Shanshan Mo#, Lanlan Yu#, Xiaolu Li, Yun Hao, Wenbo Zhang, Qi Zhang, Ping Wang, Xiangdong Wang*, Chenxuan Wang*, Luo Zhang*, Crystalline state determines the potency of galectin-10 protein assembly to induce inflammation, Nano Letters, 2022, 22(6), 2350-2357.(IF=12.262)

3. Wenbo Zhang#, Mingwei Liu#, Lanlan Yu#, Shanshan Mo, Zhun Deng, Shuli Liu, Yanlian Yang, Chen Wang, Chenxuan Wang*, Perturbation effect of single polar group substitution on the self-association of amphiphilic peptide helices, Journal of Colloid and Interface Science, 2022, 610, 1005-1014. (IF=9.965)

4. Zhichao Lou#, Qiuyi Wang, Xiaodi Zhou, Ufuoma I. Kara, Rajdeep S. Mamtani, Hualiang Lv*, Meng Zhang, Zhihong Yang, Yanjun Li, Chenxuan Wang*, Solomon Adera*, Xiaoguang Wang*, An angle-insensitive electromagnetic absorber enabling a wideband absorption, Journal of Materials Science & Technology, 2022, 113, 33-39. (IF=10.319)

5. Lanlan Yu#, Wenbo Zhang, Wendi Luo, Robert L. Dupont, Yang Xu, Yibing Wang, Bin Tu, Haiyan Xu, Xiaoguang Wang, Qiaojun Fang*, Yanlian Yang, Chen Wang, Chenxuan Wang*, Molecular recognition of human islet amyloid polypeptide assembly by selective oligomerization of thioflavin T, Science Advances, 2020, 6(32), eabc1449. (IF=14.957)

6. Chenxuan Wang#, Travis Nelson, Dayue Chen, Joseph Christopher Ellis, Nicholas L. Abbott*, Understanding Lipopolysaccharide Aggregation and its Influence on Activation of Factor C, Journal of Colloid and Interface Science, 2019, 552, 540-553. (IF=9.965)

7. Xiaoyun Li#, Zhu Liang#, Jianchao Du#, Zhiqing Wang, Song Mei, Zhiqing Li, Yan Zhao, Dandan Zhao, Yiming Ma, Jun Ye, Jiantao Xu, Yu Zhao, Jiahui Chang, Yuhao Qin, Lanlan Yu, Chenxuan Wang*, Chengyu Jiang*, Herbal decoctosome is a novel form of medicine, Science China-Life Sciences, 2019, 62(3), 333-348. (IF=10.372)

8. Chenxuan Wang#, C. Derek Ma, Hongseung Yeon, Xiaoguang Wang, Samuel H. Gellman*, Nicholas L. Abbott*, Nonadditive interactions mediated by water at chemically heterogeneous surfaces: nonionic polar groups and hydrophobic interactions, Journal of the American Chemical Society, 2017, 139(51), 18536-18544. (IF=16.383)

9. Chenxuan Wang#, Xiaobo Mao#, Aihua Yang, Lin Niu, Shengnan Wang, Denghua Li, Yuanyuan Guo, Yibin Wang, Yanlian Yang*, Chen Wang*, Determination of relative binding affinities of labeling molecules with amino acids by using scanning tunneling microscopy, Chemical Communications, 2011, 47(38), 10638-10640. (IF=6.065)

10. Xiaobo Mao#, Chenxuan Wang#, Xingkui Wu, Lei Liu, Lan Zhang, Lin Niu, Yanlian Yang*, Chen Wang*, Beta structure motifs of islet amyloid polypeptides identified through surface-mediated assemblies, Proceedings of the National Academy of Sciences of the USA, 2011, 108(49), 19605-19610. (IF=12.779)