人才建设

您所在的位置: 首页 - 人才建设 - 师资队伍 - 准聘长聘教师 - 助理教授 - 生物医学工程研究所

生物医学工程研究所

个人简介

王伟伟,1987年出生,籍贯山东安丘,生物医学材料专家,中国医学科学院生物医学工程所院研究员,博士生导师。2004年考入东北大学应用化学专业,2008年获得学士学位。2008年至2013年在天津大学大学材料化学工程专业攻读硕士和博士学位,从事药物递送水凝胶研究。2013年进入生物医学工程研究所进行博士后研究工作,主要研究纳米生物材料和仿生水凝胶材料。2015年升为助理研究员。2016年为副研究员。2020年破格获得卫健委研究员(资格)。


主要研究方向

团队面向人民生命健康,开展免疫调控生物材料的构建及其在重大疾病治疗和组织器官损伤修复中的应用基础研究。医工结合方面,研发心血管疾病治疗器械,侧重完全可吸收的结构性心脏病封堵器和心衰治疗水凝胶。


代表性成果

黄金城赌城,澳门黄金城

图片

1. Wenshuai Liu#, Rui Gao, Chunfang Yang, Zujian Feng, Wenbin Ou-Yang, Xiangbin Pan, Pingsheng Huang, Chuangnian Zhang, Deling Kong, and Weiwei Wang*. ECM-mimetic immunomodulatory hydrogel for methicillin-resistant Staphylococcus aureus–infected chronic skin wound healing. Science Advances. 2022, 8(27): eabn7006. (IF=14.136)

2. Yaping Wang#, Jingrong Wang#, Rui Gao, Xiang Liu, Zujian Feng*, Chuangnian Zhang, Pingsheng Huang, Anjie Dong*, Deling Kong, and Weiwei Wang*. Biomimetic glycopeptide hydrogel coated PCL/nHA scaffold for enhanced cranial bone regeneration via macrophage M2 polarization-induced osteo-immunomodulation. Biomaterials. 2022, 285: 121538. (IF=15.304)

3. Xiang Liu#, Xiaofei Chen#, Xinyi Chi, Zujian Feng, Chunfang Yang, Rui Gao, Shuangyang Li, Chuangnian Zhang, Xiaogang Chen*, Pingsheng Huang, Anjie Dong*, Deling Kong, and Weiwei Wang*. Biomimetic integration of tough polymer elastomer with conductive hydrogel for highly stretchable, flexible electronic. Nano Energy. 2022, 92: 106735. (IF=19.069)

4. Qi Su#, Huijuan Song*, Pingsheng Huang*, Chuangnian Zhang, Jing Yang, Deling Kong, and Weiwei Wang*. Supramolecular co-assembly of self-adjuvanting nanofibrious peptide hydrogel enhances cancer vaccination by activating MyD88-dependent NF-κB signaling pathway without inflammation. Bioactive Materials. 2021, 6(11): 3924-3934. (IF=14.119)

5. Xiang Liu#, Qi Su, Huijuan Song, Xiaoguang Shi, Yuming Zhang*, Chuangnian Zhang, Pingsheng Huang, Anjie Dong*, Deling Kong, and Weiwei Wang*. PolyTLR7/8a-conjugated, antigen-trapping gold nanorods elicit anticancer immunity against abscopal tumors by photothermal therapy-induced in situ vaccination. Biomaterials. 2021, 275: 120921. (IF=15.304)

6. Changrong Wang#, Xiaoguang Shi, Huijuan Song, Chuangnian Zhang, Xiaoli Wang, Pingsheng Huang, Anjie Dong*, Yumin Zhang*, Deling Kong, and Weiwei Wang*. Polymer-lipid hybrid nanovesicle-enabled combination of immunogenic chemotherapy and RNAi-mediated PD-L1 knockdown elicits antitumor immunity against melanoma. Biomaterials. 2021, 268: 120579. (IF=15.304, ESI)

7. Zujian Feng#, Qi Su, Chuangnian Zhang, Pingsheng Huang, Huijuan Song, Anjie Dong*, Deling Kong*, and Weiwei Wang*. Bioinspired nanofibrous glycopeptide hydrogel dressing for accelerating wound healing: A cytokine‐free, M2‐type macrophage polarization approach. Advanced Functional Materials. 2020, 30(52): 2006454. (IF=18.808)

8. Wenshuai Liu#, Wenbin Ou-Yang, Chao Zhang, Qiangsong Wang, Xiangbin Pan*, Pingsheng Huang, Chuangnian Zhang, Yuejie Li, Deling Kong*, and Weiwei Wang*. Synthetic polymeric antibacterial hydrogel for methicillin-resistant staphylococcus aureus-infected wound healing: Nanoantimicrobial self-assembly, drug and cytokine-free strategy. ACS Nano. 2020, 14(10): 12905–12917. (IF=15.881)

9. Xiang Liu#, Zujian Feng, Changrong Wang, Qi Su, Huijuan Song, Chuangnian Zhang, Pingsheng Huang, Xing-Jie Liang*, Anjie Dong*, Deling Kong, and Weiwei Wang*. Co-localized delivery of nanomedicine and nanovaccine augments the postoperative cancer immunotherapy by amplifying T-cell responses. Biomaterials. 2020, 230: 119649. (IF=12.479, ESI)

10. Pengxiang Yang#, Huijuan Song, Yibo Qin, Pingsheng Huang, Chuangnian Zhang, Deling Kong*, and Weiwei Wang*, Engineering dendritic cells-based vaccines and PD-1 blockade in self-assembled peptide nanofibrous hydrogel to amplify antitumor T-cell immunity. Nano Letters. 2018, 18(7): 4377–4385. (IF=12.279)