范武发，1989年生，籍贯福建龙岩，从事药剂学研究，中国医学科学院药物研究所研究员，博士生导师。2008年考入福建中医药大学药物制剂专业，2012年获得学士学位。2012年在郑州大学药剂学专业攻读硕士学位，2015年获得硕士学位，从事纳米药物递送研究。2015年在复旦大学药剂学专业攻读博士学位，2019年获得博士学位，从事纳米药物递送研究。2019-2022年进入北京大学化学与分子工程学院进行博士后研究工作，从事纳米药物递送研究。

生物医用高分子材料的合成与应用；纳米药物跨生物屏障递送及机制；纳米药物肿瘤免疫治疗；多肽、蛋白、核酸等大分子药物递送；纳米药物生物学效应

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1. Wufa Fan#, Qiuyu Wei, Jiajia Xiang, Yisi Tang, Quan Zhou, Yu Geng, Yanpeng Liu, Rui Sun, Lei Xu, Guowei Wang, Ying Piao, Shiqun Shao*, Zhuxian Zhou, Jianbin Tang, Tao Xie, Zichen Li*, Youqing Shen*. Mucus penetrating and cell-binding polyzwitterionic micelles as potent oral nanomedicine for cancer drug delivery. Adv Mater 34(16):e2109189. (IF=32.086)

2. Wufa Fan#, Haixia Peng, Zhou Yu, Luting Wang, Haisheng He, Yuhua Ma, Jianping Qi, Yi Lu, Wei Wu*. The long-circulating effect of pegylated nanoparticles revisited via simultaneous monitoring of both the drug payloads and nanocarriers. Acta Pharm Sin B 12(5):2479-2493. (IF=14.903)

3. Siqin Chen#, Yin Zhong#, Wufa Fan#, Jiajia Xiang#, Guowei Wang, Quan Zhou, Jinqiang Wang, Yu Geng, Rui Sun, Zhen Zhang, Ying Piao, Jianguo Wang, Jianyong Zhuo, Hailin Cong, Haiping Jiang, Jun Ling, Zichen Li, Dingding Yang, Xin Yao, Xiao Xu, Zhuxian Zhou, Jianbin Tang, Youqing Shen*. Enhanced tumour penetration and prolonged circulation in blood of polyzwitterion-drug conjugates with cell-membrane affinity. Nat Biomed Eng 5(9):1019-1037. (IF=29.234, ESI)

4. Yisi Tang#, Wufa Fan#, Guihua Chen, Meng Zhang, Xueping Tang, Hairui Wang, Pengfei Zhao, Qin Xu, Zhibing Wu*, Xiaoxi Lin, Yongzhuo Huang*. Recombinant cancer nanovaccine for targeting tumor-associated macrophage and remodeling tumor microenvironment. Nano Today 40:101244. (IF=18.962)

5. Wufa Fan#, Zhou Yu#, Haixia Peng, Haisheng He, Yi Lu, Jianping Qi, Xiaochun Dong, Weili Zhao, Wei Wu*. Effect of particle size on the pharmacokinetics and biodistribution of parenteral nanoemulsions. Int J Pharm 586:119551. (IF=5.875)

6. Zhou Yu#, Wufa Fan#, Luting Wang, Haisheng He, Yongjiu Lv, Jianping Qi, Yi Lu, Wei Wu*. Slowing down lipolysis significantly enhances the oral absorption of intact solid lipid nanoparticles. Biomater Sci 7(10):4273-4282. (IF=6.183)